Peptide Database

Peptide NameEpiregulin

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC226H343N61O69S8

DescriptionStandard

        VSITKCSSDMNGYCLHGQCIYLVDMSQNYCRCEVGYTGVRCEHFFL
    

Molecular Weight5275.03 Da

Isoelectric Point (pI)6.01

Net Charge (pH 7.0)-1.15

Net Charge (pH 7.4) -1.56

Charge Density (pH 7.0) -0.0250

GRAVY Index0.06

Hydrophobic Moment 0.53

Boman Index0.08

Instability Index8.35

Aliphatic Index 67.61

Aromaticity 0.1304

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2103.86

LogP -21.76

H-bond Donors 80.0

H-bond Acceptors 78.0

Rotatable Bonds 171.0

Heavy Atoms 364.0

Ring Count 8.0

Amide Bonds 49.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0195679 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-19; 14-30; 32-41

Bio-Activity Profile

Function

Cytokine Growth factor Growth factor signaling Angiogenic