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MYP_003157
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Basic Information
RN7
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
45 amino acids
C227H364N70O65S3
Standard
Sequence
KPKGMTSSQWFKIQHMQPSPQASNSAMKNINKHTKRSKDLNTFLH
Physicochemical Analysis
5209.94 Da
10.75
7.02
6.65
0.1559
-1.21
0.69
-0.24
61.05
39.11
0.0667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2227.31
-27.23
75.0
78.0
178.0
365.0
10.0
52.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0053732 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans ATCC 90028 (MFC100 = 0.93 ± 0.20 microM (Sabouraud Broth)), C. albicans ATCC 90028 (MFC100 = 0.93 ± 0.10 microM (PBS)), (IC50 = 0.45 ± 0.10 microM)
0.45 ± 0.10 μM
IC50
PMID31540052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31540052/
RECORD: Rec_0122920 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans ATCC 90028
PMID31540052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31540052/
RECORD: Rec_0146452 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Protein-derived peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium vaccae strain (ATCC 15483)
0.3 μM
IC50
PMID23716047 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23716047/
RECORD: Rec_0171696 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Protein-derived peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium vaccae strain (ATCC 15483)
0.8 μM
MIC
PMID23716047 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23716047/
RECORD: Rec_0230616 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID31540052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31540052/
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