‹ ›
MYP_003154
← PREVIOUS NEXT → BACK
Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
11 amino acids
C89H111N17O12
Standard
Sequence
FLWWLFKWAWK
Physicochemical Analysis
1610.94 Da
10.00
1.76
1.55
0.1598
0.33
0.43
0.49
14.51
80.00
0.5455
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
469.52
6.00
18.0
14.0
45.0
118.0
10.0
10.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0309831 VERIFIED: NO
Provenance & Taxonomy
Glandirana rugosa [Animal]
Gaegurin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
HCTl-16
14800 μM
IC50
PaperAnalogues of antimicrobial and anticancer peptide synthesized and produced from Gaegurin 5 Evidence URLhttps://patents.google.com/patent/US8076284B2/en PatentUS8076284B2
RECORD: Rec_0316679 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
S. typhimorium
200 μg/mL
MIC
PMID21110126 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21110126/
RECORD: Rec_0317729 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Cytotoxic
PC-3
24.32 μM
IC50
PaperAnticancer activity of undecapeptide analogues derived from antimicrobial peptide, brevinin-1EMa PMID22644847 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22644847/
RECORD: Rec_0323485 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin-1EMa analogue
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
Bio-Activity Profile
Anticancer
HCT-116
14.80 μM
IC50
PaperAnticancer activity of undecapeptide analogues derived from antimicrobial peptide, brevinin-1EMa; Activity optimization of an undecapeptide analogue derived from a frog-skin antimicrobial peptide; Application Value of Antimicrobial Peptides in Gastrointestinal Tumors. PMID22644847;21110126 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22644847/
RECORD: Rec_0355239 VERIFIED: NO
Provenance & Taxonomy
Glandirana rugosa [Animal]
Gaegurin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
SK-MEL-2
13160 μM
IC50
PaperNovel analogues of antimicrobial and anticancer peptide synthesized and produced from gaegurin 5 Evidence URLhttps://patents.google.com/patent/WO2007133033A1/en PatentWO2007133033A1
FIRST PREV 1 ... 6 7 8 9 10 NEXT LAST
Showing 5 records on this page · Page 8 of 10