Peptide Database

Peptide NameS-type Pyocin domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length557 amino acids

Chemical FormulaC2655H4181N753O833S19

DescriptionStandard

        MTRALVRLGDKTTSGGEVISASSTIIEGRNIALNGDMAWCPKDTCNGPFQINGTAYYFAEDKPCVATGDQVLCNCKNNQVLGSTTLWVEDSPGDPFEEHRKRAAEWPITKMAAAAAVAAIPVFAKSVLRGTGNTDAGESEEPQSNIGEMSFYQSQPAQPTPEPEQHAQAAKRKKNAPPPEPPKKSLFDKVTGFFFGEAEAMPLSPPPVVMGGTAEAGMAAAAGGATTKSNQDAAKALTHTMKRLSGPEVWSGQLAMNLPFVVMGAIIQSNLKGEQSDLLTPQNLLEVAHSKGTVPTRVRYNWITDDDSGKLKAVGYHTTAASGRDQVRVRMLEKQTDGSYEFWGDERSDKPLITWTPANTPGSQSSWNTGNNSPQAGTVTIPGLEHPDIQSVTITTTPPPEEKDFRDYILVFPGNVHPPIYIYLSKPPVELLEVDLYSNFTGRPRNGTHADHMPSAAAVRAFLRREYPDAKPAEIDRMAKDVASIIIPADIHQKLSATYGRRNSPTQIQQDSKDLRAAVDRDIETLRPALKERGVTDRQIDEAKAKMHQLNQEQGLY
    

Molecular Weight60586.38 Da

Isoelectric Point (pI)5.86

Net Charge (pH 7.0)-7.50

Net Charge (pH 7.4) -8.49

Charge Density (pH 7.0) -0.0135

GRAVY Index-0.54

Hydrophobic Moment 0.76

Boman Index-0.04

Instability Index44.82

Aliphatic Index 68.74

Aromaticity 0.0646

Extinction Coeff. Reduced 63370.00

Extinction Coeff. Oxidized 63620.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0172860 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterobacter cloacae [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)