Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length85 amino acids

Chemical FormulaC423H661N119O116S13

DescriptionStandard

        LKNHPSEMAPRRMMFYFVFTLFFILAQLPSGCQGGLDYAPLFPAGEGSVCDTCRLGRGKCRKICLENEKVEGNCMMDLFCCRERH
    

Molecular Weight9686.35 Da

Isoelectric Point (pI)8.20

Net Charge (pH 7.0)1.87

Net Charge (pH 7.4) 1.43

Charge Density (pH 7.0) 0.0220

GRAVY Index-0.09

Hydrophobic Moment 0.66

Boman Index0.01

Instability Index45.39

Aliphatic Index 65.41

Aromaticity 0.1059

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3751.27

LogP -33.14

H-bond Donors 137.0

H-bond Acceptors 133.0

Rotatable Bonds 319.0

Heavy Atoms 671.0

Ring Count 16.0

Amide Bonds 89.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0383594 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence