Peptide Database

Peptide NameColicin-E3 (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length406 amino acids

Chemical FormulaC2013H3199N561O590S10

DescriptionStandard

        MSDKHDPSDGTPHIKVTVYSTPCESEEWPSIDNFNVFQYPGRNRPSILKEYLDEARREPERMVYLSSAAAVGRSALIFPVNGTLAATIASWIQSFDFSALLAGLRDTLPLAGRITGIAALLWPTKMGNAELYQGAGPLIDLNRAKLVDMRQADMVVTLPSELVTTVKPADIRGQKTVPAMVVAQGVVDAVKQEHTVALTMAENTDIPVITAQKTKKPNVYTAEVVPGMKPLRIRMVSPSGKQVPPSKSVELPAAEHYLPQPDSGKTHHAFIVFGDDYQPVYISVTRKEWQVKPYVEAKKAEEEKKRQGVKDKGHSYHPEPDVEEIKGLGELKPGKKKTPKQGGAGKRARWVGDKGRKIYEWDYQHGELEGYRASDGQHLGAFDPKTGKQLKPADPERNIKKIFIRR
    

Molecular Weight45019.99 Da

Isoelectric Point (pI)9.23

Net Charge (pH 7.0)9.41

Net Charge (pH 7.4) 8.54

Charge Density (pH 7.0) 0.0232

GRAVY Index-0.55

Hydrophobic Moment 0.73

Boman Index-0.06

Instability Index35.08

Aliphatic Index 77.34

Aromaticity 0.0714

Extinction Coeff. Reduced 53860.00

Extinction Coeff. Oxidized 53860.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0057910 VERIFIED: NO

Provenance & Taxonomy

OrganismMorganella morganii [Bacterium]

FamilyColicin/Bacteriocin

Tax ID582

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence