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MYP_003093
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Basic Information
HBD10
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
35 amino acids
C164H269N59O51S6
Standard
Sequence
RECRIGNGQCKNQCHENEIRIAYCIRPGTHCCLQQ
Physicochemical Analysis
4075.65 Da
8.35
1.88
1.48
0.0538
-0.84
0.51
-0.28
47.30
58.57
0.0286
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1828.90
-23.16
68.0
61.0
138.0
280.0
4.0
41.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0128776 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
M tuberculosis H37Rv
11.8 μM
MIC
PMID31325337 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31325337/
RECORD: Rec_0144251 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-31; 10-24; 14-32
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0185457 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
M. tuberculosis H37Rv
11.8 μM
MIC
PaperAntimicrobial activity and structure of a consensus human beta-defensin and its comparison to a novel putative hBD10
RECORD: Rec_0216407 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
S aureus 25923
25 μM
MIC
PMID31325337 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31325337/
RECORD: Rec_0245299 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
E coli 25922
25 μM
MIC
PMID31325337 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31325337/
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