Peptide Database

Peptide NameNeutrophil beta-defensin 4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length63 amino acids

Chemical FormulaC306H516N100O74S7

DescriptionStandard

        MRLHHLLLVLLFVVLSSVSGFTQGIRSPLSCRGNRGVCLPIRCPGRLRQIGTCFGPRVPCCRR
    

Molecular Weight7004.45 Da

Isoelectric Point (pI)11.63

Net Charge (pH 7.0)9.62

Net Charge (pH 7.4) 9.21

Charge Density (pH 7.0) 0.1526

GRAVY Index0.38

Hydrophobic Moment 0.68

Boman Index0.02

Instability Index47.93

Aliphatic Index 108.10

Aromaticity 0.0476

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2770.81

LogP -27.30

H-bond Donors 107.0

H-bond Acceptors 93.0

Rotatable Bonds 226.0

Heavy Atoms 487.0

Ring Count 10.0

Amide Bonds 65.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0096347 VERIFIED: YES

Provenance & Taxonomy

OrganismBubalus bubalis [Animal]

FamilyDefensin

Tax ID89462

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal