Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC362H586N104O89S8

DescriptionStandard

        MKLLLLTLATLLLLSQLTPGDTQKCWNFHGKCRYRCHRKERVYVYCTNTKMCCVKPKYQPKQKHRLF
    

Molecular Weight8075.69 Da

Isoelectric Point (pI)9.89

Net Charge (pH 7.0)11.69

Net Charge (pH 7.4) 11.22

Charge Density (pH 7.0) 0.1745

GRAVY Index-0.47

Hydrophobic Moment 0.38

Boman Index-0.15

Instability Index17.32

Aliphatic Index 78.51

Aromaticity 0.1045

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3158.73

LogP -24.44

H-bond Donors 118.0

H-bond Acceptors 112.0

Rotatable Bonds 271.0

Heavy Atoms 563.0

Ring Count 14.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0168872 VERIFIED: NO

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyDefensin

Tax ID9986

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence