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MYP_002971
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Basic Information
Andersonin-W2 (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Standard
17 amino acids
C91H139N25O19S2
Standard
Sequence
AVNIPFKVHFRCKAAFC
Physicochemical Analysis
1951.36 Da
9.51
2.86
2.59
0.1683
0.65
0.38
0.17
24.96
74.71
0.1765
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
705.84
-3.97
26.0
25.0
60.0
137.0
5.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0295338 VERIFIED: YES
Provenance & Taxonomy
Odorrana andersonii [Animal]
Ranatuerin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
12-17
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
10.35 μM
MIC
PaperX. Yang et al. / Journal of Proteome Research 11 (2012) 306-319. Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs PMID22029824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22029824/
RECORD: Rec_0295488 VERIFIED: YES
Provenance & Taxonomy
Odorrana andersonii [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
12-17
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
human red blood cells
PaperExtremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs. J Proteome Res. 2012 Jan 1;11(1):306-19. doi: 10.1021/pr200782u. PMID: 22029824. PMID22029824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22029824/
RECORD: Rec_0328769 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 17.6%, E 0.0%, T 17.6%, C 64.7% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0338291 VERIFIED: NO
Provenance & Taxonomy
Odorrana andersonii [Animal] [Animal]; Odorrana wuchanensis [Animal] [Animal]; Odorrana margaratae [Animal] [Animal]; Odorrana schmackeri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0339831 VERIFIED: YES
Provenance & Taxonomy
Odorrana andersonii [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Bacillus pyocyaneus CMCCB 10104
40.4 μg/mL
MIC
PMID22029824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22029824/
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