Peptide Database

Peptide NamePhormia defensin B

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC157H262N52O48S6

DescriptionStandard

        SCDLLSGLGVNHSVCAAHCLLLGKSGGYCDRGICRCR
    

Molecular Weight3838.47 Da

Isoelectric Point (pI)8.31

Net Charge (pH 7.0)1.58

Net Charge (pH 7.4) 1.18

Charge Density (pH 7.0) 0.0426

GRAVY Index0.35

Hydrophobic Moment 0.55

Boman Index0.08

Instability Index23.98

Aliphatic Index 94.86

Aromaticity 0.0270

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1598.84

LogP -20.51

H-bond Donors 64.0

H-bond Acceptors 58.0

Rotatable Bonds 127.0

Heavy Atoms 263.0

Ring Count 3.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0004752 VERIFIED: YES

Provenance & Taxonomy

OrganismMusca domestica [Animal]

FamilyDefensin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)