Peptide Database

Peptide NameMesencephalic astrocyte-derived neurotrophic factor

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length158 amino acids

Chemical FormulaC802H1304N218O242S10

DescriptionStandard

        LRPGDCEVCISYLGRFYQDLKDRDVTFSPATIEEELIKFCREARGKENRLCYYIGATDDAATKIINEVSKPLAHHIPVEKICEKLKKKDSQICELKYDNQIDLSTVDLKKLRVKELKKILDDWGEMCKGCAEKSDYIRKINELMPKYAPKAASARTDL
    

Molecular Weight18192.90 Da

Isoelectric Point (pI)8.09

Net Charge (pH 7.0)1.88

Net Charge (pH 7.4) 1.39

Charge Density (pH 7.0) 0.0119

GRAVY Index-0.57

Hydrophobic Moment 0.75

Boman Index-0.16

Instability Index30.45

Aliphatic Index 87.09

Aromaticity 0.0696

Extinction Coeff. Reduced 15930.00

Extinction Coeff. Oxidized 16430.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7506.58

LogP -64.89

H-bond Donors 267.0

H-bond Acceptors 256.0

Rotatable Bonds 631.0

Heavy Atoms 1272.0

Ring Count 20.0

Amide Bonds 164.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0078638 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyARMET family

Tax ID10090; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-93; 9-82; 40-51; 127-130

Other Mods52-Tyr: Phosphotyrosine

Bio-Activity Profile

Function

Cytokine Growth factor ARMET family