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MYP_002948
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Basic Information
ACE inhibitory peptide
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Standard
9 amino acids
C52H100N24O12
Standard
Sequence
QQRRLLRRK
Physicochemical Analysis
1253.50 Da
12.00
4.76
4.55
0.5288
-2.37
0.58
-1.24
178.98
86.67
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
655.92
-6.92
25.0
17.0
47.0
88.0
0.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006370 VERIFIED: YES
Provenance & Taxonomy
Phaseolus vulgaris [Plant]
Bioactive peptides
3885
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme
0.095 μM
IC50
PaperImpact of commercial precooking of common bean (Phaseolus vulgaris) on the generation of peptides, after pepsin-pancreatin hydrolysis, capable to inhibit dipeptidyl peptidase-IV PMID25495131 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25495131/
RECORD: Rec_0221641 VERIFIED: YES
Provenance & Taxonomy
Phaseolus vulgaris [Plant]
3885.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic DPP-IV inhibitory
Dipeptidyl peptidase IV
PaperMojica L., Chen K., de Mejia E.G.. Impact of Commercial Precooking of Common Bean (Phaseolus vulgaris) on the Generation of Peptides, After Pepsin-Pancreatin Hydrolysis, Capable to Inhibit Dipeptidyl Peptidase-IV. Journal of Food Science, 80, 188-198, DOI: 10.1111/1750-3841.12726. PMID25495131 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25495131/
RECORD: Rec_0250067 VERIFIED: YES
Provenance & Taxonomy
Phaseolus vulgaris [Plant]
3885.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
PaperMojica L., Chen K., de Mejia E.G.. Impact of Commercial Precooking of Common Bean (Phaseolus vulgaris) on the Generation of Peptides, After Pepsin-Pancreatin Hydrolysis, Capable to Inhibit Dipeptidyl Peptidase-IV. Journal of Food Science, 80, 188-198, DOI: 10.1111/1750-3841.12726. PMID25495131 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25495131/