Peptide Database

Peptide NameHepcidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC430H677N123O125S14

DescriptionStandard

        MKAFSIAVAVTLVLAFICILESSAVPFTGVQELEEAGSNDTPVAAHQEMSMESWMMPDHIRQKRQSHLSLCRWCCNCCRGNRGCGFCCKF
    

Molecular Weight10018.63 Da

Isoelectric Point (pI)6.79

Net Charge (pH 7.0)-0.31

Net Charge (pH 7.4) -0.83

Charge Density (pH 7.0) -0.0035

GRAVY Index0.14

Hydrophobic Moment 0.66

Boman Index0.08

Instability Index60.39

Aliphatic Index 71.56

Aromaticity 0.0778

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3954.59

LogP -40.92

H-bond Donors 146.0

H-bond Acceptors 142.0

Rotatable Bonds 329.0

Heavy Atoms 692.0

Ring Count 15.0

Amide Bonds 96.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0086225 VERIFIED: NO

Provenance & Taxonomy

OrganismMyripristis murdjan [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal