Peptide Database

Peptide NameI9A-piscidin-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC119H181N37O25

DescriptionStandard

        FFHHIFRGAVHVGKTIHRLVTG
    

Molecular Weight2529.94 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)3.11

Net Charge (pH 7.4) 2.70

Charge Density (pH 7.0) 0.1413

GRAVY Index0.33

Hydrophobic Moment 0.73

Boman Index0.20

Instability Index11.97

Aliphatic Index 97.27

Aromaticity 0.1364

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 979.42

LogP -6.39

H-bond Donors 36.0

H-bond Acceptors 32.0

Rotatable Bonds 80.0

Heavy Atoms 181.0

Ring Count 7.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0393283 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyPleurocidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

Activity3.1 μg/mL

MethodMIC

RECORD: Rec_0398637 VERIFIED: YES