Peptide Database

Peptide NameJMV641

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC41H53N11O9

DescriptionStandard

        FQWAVGH
    

Molecular Weight843.93 Da

Isoelectric Point (pI)6.74

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0218

GRAVY Index0.11

Hydrophobic Moment 0.23

Boman Index0.42

Instability Index-25.03

Aliphatic Index 55.71

Aromaticity 0.2857

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 325.48

LogP -1.19

H-bond Donors 11.0

H-bond Acceptors 10.0

Rotatable Bonds 23.0

Heavy Atoms 61.0

Ring Count 4.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0133505 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitymixed L/D or modified amino-acid peptide [Mixed]

C-TermHis-NH-CH[CH2-CH(CH3)2]-CHOH-(CH2)3-CH3

Other ModsD-Phe at position 1; C-terminal histidine modified to His-NH-CH[CH2-CH(CH3)2]-CHOH-(CH2)3-CH3

Bio-Activity Profile

Function

Receptor antagonist Signaling peptide

TargetBB2 receptor (Mouse)

Activity0.46 nM

MethodIC50