Peptide Database

Peptide NameUnnamed

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC206H315N59O61S2

DescriptionStandard

        SYSMEHFRWGKPVGRKRRPVKVYTSNGVEEESAEVFPGEM
    

Molecular Weight4658.19 Da

Isoelectric Point (pI)8.13

Net Charge (pH 7.0)0.56

Net Charge (pH 7.4) 0.28

Charge Density (pH 7.0) 0.0140

GRAVY Index-0.97

Hydrophobic Moment 0.68

Boman Index-0.19

Instability Index61.22

Aliphatic Index 38.75

Aromaticity 0.1250

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1950.48

LogP -18.92

H-bond Donors 69.0

H-bond Acceptors 65.0

Rotatable Bonds 152.0

Heavy Atoms 328.0

Ring Count 10.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0048136 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0211631 VERIFIED: NO

Provenance & Taxonomy

OrganismThunnus obesus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone

RECORD: Rec_0248742 VERIFIED: NO

Provenance & Taxonomy

OrganismThunnus obesus [Animal]

FamilyPOMC

Tax ID8241

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone precursor Neuropeptide precursor

RECORD: Rec_0356993 VERIFIED: NO

Provenance & Taxonomy

OrganismThunnus obesus [Animal]

FamilyCorticotropin

Tax ID8241

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour