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MYP_002810
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Basic Information
SARSWW-I(770-788)
Antimicrobial
Antiviral
Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
18 amino acids
C105H149N23O25S
Standard
Sequence
MWKTPTLKYFGGFNFSQI
Physicochemical Analysis
2165.51 Da
9.70
1.50
1.28
0.0832
-0.17
0.25
0.22
13.93
43.33
0.2778
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
784.16
-4.19
27.0
28.0
67.0
154.0
7.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0073662 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
SARS-CoV; Vero E6 cells
58 %
Plaque assay
PaperPubMed PMID: 16616792 PMID16616792 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16616792/
RECORD: Rec_0096080 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0175839 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
SARS-CoV-2
PMID34591335 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34591335/
RECORD: Rec_0204960 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-SARS-COV Entry inhibition
SARS-CoV; Vero E6 cells
58 %
Plaque assay
Mammalian: 30 h; Yeast: >20 h; E. coli: >10 h
PaperInhibition of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infectivity by peptides analogous to the viral spike protein. | Sainz B Jr, Mossel EC, Gallaher WR, Wimley WC, Peters CJ, Wilson RB, Garry RF. | Virus Res. 2006 Sep;120(1-2):146-55. | DOI:10.1016/j.virusres.2006.03.001 | PMID:16616792 PMID16616792 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16616792/
RECORD: Rec_0358337 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Vero E6 cells
>30 μM
Cytotoxicity assay
PaperPubMed PMID: 16616792 PMID16616792 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16616792/
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