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MYP_002788
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Basic Information
Temporin-RI-SHf
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
8 amino acids
C57H77N11O10
Standard
Sequence
FIRSLFFF
Physicochemical Analysis
1076.29 Da
9.75
0.76
0.56
0.0950
1.77
0.55
0.56
63.67
97.50
0.5000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
349.15
1.11
13.0
11.0
32.0
78.0
4.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0086988 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID26181487 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26181487/
RECORD: Rec_0137527 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial
Human acute monocytic leukemia THP-1
200 μM
IC50
PMID26181487 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26181487/
RECORD: Rec_0160652 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Hemolytic
Human embryonic kidney HEK293 cells (IC50 at >200 microM, Human embryonic kidney HEK293 cells (IC50 at >200 microM
293 μM
Hemolysis
PMID26181487 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26181487/
RECORD: Rec_0188463 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
100 μM
MIC
PMID26181487 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26181487/
RECORD: Rec_0190316 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
100 μM
MIC
PMID26181487 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26181487/
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