Peptide Database

Peptide NameDefensin-like protein 195

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC291H446N88O89S8

DescriptionStandard

        QGNECLKEYGGDVGFGFCAPRIFPTICYTRCRENKGAKGGRCRWGQGSNVKCLCDFCDDTPQ
    

Molecular Weight6857.71 Da

Isoelectric Point (pI)8.19

Net Charge (pH 7.0)1.69

Net Charge (pH 7.4) 1.35

Charge Density (pH 7.0) 0.0272

GRAVY Index-0.63

Hydrophobic Moment 0.52

Boman Index-0.13

Instability Index37.76

Aliphatic Index 37.74

Aromaticity 0.1129

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2882.44

LogP -34.75

H-bond Donors 107.0

H-bond Acceptors 99.0

Rotatable Bonds 224.0

Heavy Atoms 476.0

Ring Count 11.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0015432 VERIFIED: YES

Provenance & Taxonomy

OrganismArabidopsis thaliana [Plant]

FamilyDEFL family

Tax ID3702; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide5-57; 18-42; 27-52; 31-54

Bio-Activity Profile

Function

Antimicrobial DEFL family Antifungal Ion channel inhibitor Host defense

RECORD: Rec_0121174 VERIFIED: YES

Provenance & Taxonomy

OrganismArabidopsis thaliana [Plant]

FamilyDefensin

Tax ID3702

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideDisulfide bond(s) reported

Bio-Activity Profile

Function

Antimicrobial Antifungal

PaperTwo large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response. Plant Mol Biol. 2001 May;46(1):17-34. doi: 10.1023/a:1010664704926. PMID: 11437247. | Genome organization of more than 300 defensin-like genes in Arabidopsis. Plant Physiol. 2005 Jun;138(2):600-10. doi: 10.1104/pp.105.060079. PMID: 15955924. | PubMed PMID: 12369816 PMID11437247;15955924;12369816 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11437247/