Peptide Database

Peptide NameRegenerating islet-derived protein 3-alpha (REG-3-alpha) (Islet of Langerhans regenerating protein 3) (REG 3) (Lithostathine 3) (Pancreatitis-associated protein 2) (RegIII) (Regenerating islet-derived protein III-alpha) (Reg III-alpha) [Cleaved into: Regenerating islet-derived protein 3-alpha 16.5 kDa form; Regenerating islet-derived protein 3-alpha 15 kDa form]

Function Ontology

Antimicrobial

Binding / Molecular interaction ▸ Carbohydrate-binding peptide ▸ Lectin

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length174 amino acids

Chemical FormulaC876H1315N237O259S9

DescriptionStandard

        MLPRLSFNNVSWTLLYYLFIFQVRGEDSQKAVPSTRTSCPMGSKAYRSYCYTLVTTLKSWFQADLACQKRPSGHLVSILSGGEASFVSSLVTGRVNNNQDIWIWLHDPTMGQQPNGGGWEWSNSDVLNYLNWDGDPSSTVNRGNCGSLTATSEFLKWGDHHCDVELPFVCKFKQ
    

Molecular Weight19598.83 Da

Isoelectric Point (pI)6.88

Net Charge (pH 7.0)-0.20

Net Charge (pH 7.4) -0.74

Charge Density (pH 7.0) -0.0011

GRAVY Index-0.33

Hydrophobic Moment 0.47

Boman Index0.05

Instability Index32.79

Aliphatic Index 70.52

Aromaticity 0.1264

Extinction Coeff. Reduced 52940.00

Extinction Coeff. Oxidized 53315.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7973.20

LogP -84.63

H-bond Donors 283.0

H-bond Acceptors 272.0

Rotatable Bonds 626.0

Heavy Atoms 1381.0

Ring Count 42.0

Amide Bonds 192.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0356597 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Lectin Non-hemolytic

TargetNo Target Organism Found