Peptide Database

Peptide NamePleurain-A3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC356H590N96O103S6

DescriptionStandard

        MFTLKKTLLLLFFLGTISISLCKQARDADEDDGRKMTEEEVKRSIITMTREAKLPQLWKQIACRLYNTC
    

Molecular Weight8055.46 Da

Isoelectric Point (pI)8.93

Net Charge (pH 7.0)2.48

Net Charge (pH 7.4) 2.20

Charge Density (pH 7.0) 0.0360

GRAVY Index-0.20

Hydrophobic Moment 0.65

Boman Index-0.07

Instability Index55.53

Aliphatic Index 94.78

Aromaticity 0.0725

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3271.35

LogP -27.23

H-bond Donors 119.0

H-bond Acceptors 112.0

Rotatable Bonds 281.0

Heavy Atoms 561.0

Ring Count 7.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0389246 VERIFIED: NO

Provenance & Taxonomy

OrganismNidirana pleuraden [Animal]

FamilyFrog skin active peptide (FSAP)

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic Non-ribosomal

TargetGram-negative bacteria; Gram-positive bacteria

MethodQualitative functional evidence