Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length105 amino acids

Chemical FormulaC523H827N145O146S8

DescriptionStandard

        MKLQLVAFSVFVFLLQVIPAYGDGRKCRNKLGTCRKHCKYGEAIKEVCKNHRICCISASKSHSQGAFDKILPKATPTTWYDLPSGAFDVIMTVPAANRFEENVND
    

Molecular Weight11738.57 Da

Isoelectric Point (pI)9.13

Net Charge (pH 7.0)5.71

Net Charge (pH 7.4) 5.22

Charge Density (pH 7.0) 0.0544

GRAVY Index-0.14

Hydrophobic Moment 0.64

Boman Index0.01

Instability Index30.43

Aliphatic Index 78.95

Aromaticity 0.0952

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4680.94

LogP -44.36

H-bond Donors 167.0

H-bond Acceptors 163.0

Rotatable Bonds 388.0

Heavy Atoms 822.0

Ring Count 19.0

Amide Bonds 112.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0025342 VERIFIED: NO

Provenance & Taxonomy

OrganismFukomys damarensis [Animal]

FamilyBeta-defensin; Defensin

Tax ID885580

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic