Peptide Database

Peptide NameUnnamed

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Standard StatusStandard

Sequence Length5 amino acids

Chemical FormulaC25H44N8O8

DescriptionStandard

        APLER
    

Molecular Weight584.67 Da

Isoelectric Point (pI)6.05

Net Charge (pH 7.0)-0.20

Net Charge (pH 7.4) -0.39

Charge Density (pH 7.0) -0.0403

GRAVY Index-0.80

Hydrophobic Moment 0.59

Boman Index-0.29

Instability Index46.52

Aliphatic Index 98.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 270.13

LogP -1.96

H-bond Donors 9.0

H-bond Acceptors 8.0

Rotatable Bonds 17.0

Heavy Atoms 41.0

Ring Count 1.0

Amide Bonds 4.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0343255 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antidiabetic DPP-IV inhibitory

TargetDipeptidyl peptidase IV

Activity63.67

MethodIC50

PaperHarnedy-Rothwell P. A., McLaughlin C. M., O¡¯Keeffe M. B., le Gouic A. v., Allsopp P. J., McSorley E. M., Sharkey S., Whooley J., McGovern B., et al.. Identification and characterisation of peptides from a boarfish (capros aper) protein hydrolysate displaying in vitro dipeptidyl peptidase-IV (DPP-IV) inhibitory and insulinotropic activity. Food Research International, 131, 108989, 2020.