Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC359H600N100O91S9

DescriptionStandard

        MKLFLVLIILQFEVPTDTARPRKCFSNITGYCRKKCKMGEIYEMACLNGKLCCVNVLELRARRKIAKPPP
    

Molecular Weight8061.80 Da

Isoelectric Point (pI)9.65

Net Charge (pH 7.0)8.44

Net Charge (pH 7.4) 8.12

Charge Density (pH 7.0) 0.1206

GRAVY Index0.02

Hydrophobic Moment 0.60

Boman Index-0.04

Instability Index45.65

Aliphatic Index 94.71

Aromaticity 0.0714

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3087.07

LogP -22.39

H-bond Donors 113.0

H-bond Acceptors 109.0

Rotatable Bonds 272.0

Heavy Atoms 559.0

Ring Count 10.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0079947 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyDefensin

Tax ID9615

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal