Peptide Database

Peptide NameZinc finger CCCH-type antiviral protein 1

Function Ontology

Antiviral

Antiviral ▸ Anti-Filovirus ▸ Anti-Ebola virus

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length776 amino acids

Chemical FormulaC3769H5927N1113O1166S40

DescriptionStandard

        MADPGVCCFITKILCAHGGRMTLEELLGEIRLPEAQLYELLETAGPDRFVLLETGGQAGITRSVVATTRARVCRRKYCQRPCDSLHLCKLNLLGRCHYAQSQRNLCKYSHDVLSEQNFQILKNHELSGLNQEELACLLVQSDPFFLPEICKSYKGEGRKQTCGQPQPCERLHICEHFTRGNCSYLNCLRSHNLMDRKVLTIMREHGLSPDVVQNIQDICNNKHARRNPPGTRAAHPHRRGGAHRDRSKSRDRFLHNSLEFLSPVVSPLGSGPPSPDVTSCKDSLEDVSVDVTQKFKYLGTHDRAQLSPVSSKAAGVQGPSQMRASQEFSEDGNLDDIFSRNRSDSSSSRASAAKVAQRNEAVAMKMGMEVKGKKEAPDIDRVPFLNSYIDGVTMEKASVSGIPGKKFTANDLENLLLLNDTWKNVAKPQDLQTTGRITDSGQDKAFLQNKYGGNPVWASASTHNAPNGSSQIMDETPNVSKSSTSGFAIKPAIAGGKEAVYSGVQSPRSQVLAVPGEATTPVQSNRLPQSPLSSSSHRAAASGSPGKNSTHTSVSPAIESSRMTSDPDEYLLRYILNPLFRMDNHGPKEICQDHLYKGCQQSHCDRSHFHLPYRWQMFVYTTWRDFQDMESIEQAYCDPHVELILIENHQINFQKMTCDSYPIRRLSTPSYEEKPLSAVFATKWIWYWKNEFNEYIQYGNESPGHTSSDINSAYLESFFQSCPRGVLPFQAGSQKYELSFQGMIQTNIASKTQRHVVRRPVFVSSNDVEQKRRGPE
    

Molecular Weight86769.74 Da

Isoelectric Point (pI)8.46

Net Charge (pH 7.0)9.73

Net Charge (pH 7.4) 7.60

Charge Density (pH 7.0) 0.0125

GRAVY Index-0.61

Hydrophobic Moment 0.72

Boman Index-0.10

Instability Index53.41

Aliphatic Index 68.49

Aromaticity 0.0735

Extinction Coeff. Reduced 72770.00

Extinction Coeff. Oxidized 74270.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0009034 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyZAP

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPhosphorylation Ser257, Ser262, Ser266, Ser270, Ser274, Ser283, Ser325, Ser351, Ser398, Ser544, Ser667

Bio-Activity Profile

Function

Antiviral Translation regulator Interferon pathway modulator Anti-SINV

TargetSindbis virus (SINV)

RECORD: Rec_0010506 VERIFIED: YES