Peptide Database

Peptide NameHalictine-2/11, HAL-2/11

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC70H118N18O14

DescriptionStandard

        GKWLSLLKHILK
    

Molecular Weight1435.80 Da

Isoelectric Point (pI)10.30

Net Charge (pH 7.0)2.84

Net Charge (pH 7.4) 2.59

Charge Density (pH 7.0) 0.2370

GRAVY Index0.23

Hydrophobic Moment 0.65

Boman Index0.15

Instability Index50.89

Aliphatic Index 162.50

Aromaticity 0.0833

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 526.18

LogP -0.34

H-bond Donors 19.0

H-bond Acceptors 18.0

Rotatable Bonds 50.0

Heavy Atoms 102.0

Ring Count 3.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0389192 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer Cytotoxic

TargetHuman cervical carcinoma HeLa S3

Activity14

MethodIC50

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