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MYP_002610
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Basic Information
Mutacin-1140 (Mutacin III; Bacteriocin)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
22 amino acids
C104H152N28O31S4
Standard
Sequence
FKSWSLCTPGCARTGSFNSYCC
Physicochemical Analysis
2418.75 Da
8.53
1.72
1.45
0.0781
0.00
0.24
0.08
13.67
22.27
0.1818
6990.00
7240.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
954.04
-12.71
39.0
37.0
72.0
167.0
6.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0061757 VERIFIED: YES
Provenance & Taxonomy
Streptococcus mutans [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0071449 VERIFIED: YES
Provenance & Taxonomy
Streptococcus mutans [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
S. salivarius ATCC 25975
PMID9596742 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9596742/
RECORD: Rec_0083359 VERIFIED: YES
Provenance & Taxonomy
Streptococcus mutans [Bacterium]
Bacteriocin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
mutans OMZ175
PaperPubMed PMID: 11082191 PMID11082191 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11082191/
RECORD: Rec_0089017 VERIFIED: YES
Provenance & Taxonomy
Streptococcus mutans [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
S. salivarius ATCC 27945
PMID9596742 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9596742/
RECORD: Rec_0094621 VERIFIED: YES
Provenance & Taxonomy
Streptococcus mutans [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
S. mutans OMZ175
PMID9596742 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9596742/
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