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MYP_002599
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Basic Information
Temporin-1Ob
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C70H120N14O15
Standard
Sequence
FLPLIGKILGTIL
Physicochemical Analysis
1397.79 Da
8.75
0.76
0.55
0.0584
1.88
0.49
0.70
34.08
210.00
0.0769
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
449.98
1.06
15.0
16.0
45.0
99.0
2.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0005527 VERIFIED: YES
Provenance & Taxonomy
Rana ornativentris [Animal]
Temporin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
5.0 μM
MIC
PaperJ.B. Kim et al. / The Journal of Peptide Research 58 (2008) 349-356. Antimicrobial peptides from the skin of the Japanese mountain brown frog, Rana ornativentris Evidence URLhttps://www.uniprot.org/uniprotkb/A0ZT59/entry
RECORD: Rec_0023737 VERIFIED: NO
Provenance & Taxonomy
Rana ornativentris [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic
RECORD: Rec_0104919 VERIFIED: YES
Provenance & Taxonomy
Rana ornativentris [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
150 μM
MIC
PMID11892844 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11892844/
RECORD: Rec_0125279 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0252416 VERIFIED: NO
Provenance & Taxonomy
Montane brown [Animal]
Temporin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
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