Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC557H884N146O169S3

DescriptionStandard

        PDLSGYEKYGLGNVKYNISRIHITAVEFPGASISLIPETGIKLVIGNASLTIDMNWNIRTWMFKDSGRSTVYISKVFVTAIFSTPLDNTGHPSISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12426.05 Da

Isoelectric Point (pI)8.89

Net Charge (pH 7.0)2.13

Net Charge (pH 7.4) 1.93

Charge Density (pH 7.0) 0.0187

GRAVY Index-0.02

Hydrophobic Moment 0.53

Boman Index0.12

Instability Index21.19

Aliphatic Index 94.04

Aromaticity 0.0877

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 16960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5045.15

LogP -53.84

H-bond Donors 180.0

H-bond Acceptors 176.0

Rotatable Bonds 408.0

Heavy Atoms 875.0

Ring Count 19.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0148593 VERIFIED: NO

Provenance & Taxonomy

OrganismAegotheles bennettii [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria