MYP_002585
Basic Information
Tat-C-Cy5
Delivery / Targeting Cell penetration Cell-penetrating peptide
Delivery / Targeting Drug delivery vehicle
Standard
12 amino acids
C67H123N33O15S
Standard
Sequence
YGRKKRRQRRRC
Physicochemical Analysis
1662.97 Da
12.00
7.75
7.53
0.6456
-3.12
0.49
-1.50
188.51
0.00
0.0833
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
870.18
-10.66
36.0
24.0
61.0
116.0
1.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0363392 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
Tat
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Cysteine addition
C-terminal cysteine conjugated to Cy5 fluorochrome
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
F98 rat glioma cells; CHO cells
Confocal fluorescence microscopy; flow cytometry (cell penetration)
RECORD: Rec_0425857 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Tat
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
None
DSPE-PEG(2000) conjugation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
bovine chondrocytes; bovine cartilage explants
Flow cytometry (chondrocyte association); fluorescence cartilage-diffusion assay