Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length85 amino acids

Chemical FormulaC393H667N119O112S10

DescriptionStandard

        MALSTRIQAACLLLLLLASVASVSVLPHQTGQLTDLRAQDTAGAEAGLQPTLQLRRLRRRDTHFPICIFCCGCCKTPKCGLCCKT
    

Molecular Weight9171.88 Da

Isoelectric Point (pI)9.04

Net Charge (pH 7.0)5.59

Net Charge (pH 7.4) 5.13

Charge Density (pH 7.0) 0.0657

GRAVY Index0.32

Hydrophobic Moment 0.64

Boman Index0.06

Instability Index55.76

Aliphatic Index 103.41

Aromaticity 0.0235

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3691.78

LogP -40.05

H-bond Donors 139.0

H-bond Acceptors 130.0

Rotatable Bonds 303.0

Heavy Atoms 634.0

Ring Count 8.0

Amide Bonds 90.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0167924 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyHepcidin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEscherichia coli

RECORD: Rec_0174789 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyHepcidin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetN. cinerea

RECORD: Rec_0185159 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyHepcidin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus

RECORD: Rec_0415235 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyHepcidin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus epidermidis