Peptide Database

Peptide NameTumor necrosis factor ligand superfamily member 4

Function Ontology

Anticancer ▸ tumor necrosis factor family

Immunology ▸ Chemokine signaling ▸ Chemokine-like peptide

Immunology ▸ Immune modulation ▸ Cytokine modulation

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length133 amino acids

Chemical FormulaC695H1090N180O208S4

DescriptionStandard

        QVSHRYPRIQSIKVQFTEYKKEKGFILTSQKEDEIMKVQNNSVIINCDGFYLISLKGYFSQEVNISLHYQKDEEPLFQLKKVRSVNSLMVASLTYKDKVYLNVTTDNTSLDDFHVNGGELILIHQNPGEFCVL
    

Molecular Weight15423.43 Da

Isoelectric Point (pI)6.47

Net Charge (pH 7.0)-0.90

Net Charge (pH 7.4) -1.38

Charge Density (pH 7.0) -0.0067

GRAVY Index-0.35

Hydrophobic Moment 0.47

Boman Index-0.01

Instability Index30.34

Aliphatic Index 94.36

Aromaticity 0.1053

Extinction Coeff. Reduced 10430.00

Extinction Coeff. Oxidized 10555.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6348.75

LogP -57.87

H-bond Donors 216.0

H-bond Acceptors 215.0

Rotatable Bonds 527.0

Heavy Atoms 1087.0

Ring Count 21.0

Amide Bonds 150.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0300575 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Familytumor necrosis factor family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide47-131

Bio-Activity Profile

Function

Cytokine Growth factor tumor necrosis factor family Chemokine-like Host defense