Peptide Database

Peptide Namehepcidin TH1-5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC92H150N30O24S8

DescriptionStandard

        GIKCRFCCGCCNAGVCGLCCRF
    

Molecular Weight2316.88 Da

Isoelectric Point (pI)8.54

Net Charge (pH 7.0)2.68

Net Charge (pH 7.4) 2.36

Charge Density (pH 7.0) 0.1218

GRAVY Index1.00

Hydrophobic Moment 0.40

Boman Index0.16

Instability Index1.83

Aliphatic Index 53.18

Aromaticity 0.0909

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 867.33

LogP -10.67

H-bond Donors 39.0

H-bond Acceptors 35.0

Rotatable Bonds 74.0

Heavy Atoms 154.0

Ring Count 2.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0242526 VERIFIED: YES

Provenance & Taxonomy

OrganismHaplochromis nyererei [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)