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MYP_002499
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Basic Information
Transferrin receptor (TfR)-lytic hybrid peptide
Anticancer
Antimicrobial
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
32 amino acids
C179H303N47O35S
Standard
Sequence
THRPPMWSPVWPGGGKLLLKLLKKLLKLLKKK
Physicochemical Analysis
3705.68 Da
11.51
8.48
8.22
0.2649
-0.30
0.84
-0.01
22.95
118.75
0.0625
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1301.04
-2.75
45.0
46.0
125.0
262.0
9.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0275953 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Transferrin receptor-targeting peptide
7370
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
ZR75-1
9.3 μM
IC50 (WST-8 cell viability assay)
PMID21849092 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21849092/
RECORD: Rec_0277067 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Transferrin receptor-targeting peptide
7370
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
SN-19
7.8 μM
IC50 (WST-8 cell viability assay)
PMID21849092 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21849092/
RECORD: Rec_0289233 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Anticancer
TfR-expressing cancer cell lines
WST-8 cell viability assay
PaperPatent US 2011/0319336 A1 PMID21849092 Evidence URLhttps://patents.google.com/patent/US20110319336A1/en PatentUS 2011/0319336 A1
RECORD: Rec_0290223 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Transferrin receptor-targeting peptide
7370
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
BT-20
4.8 μM
IC50 (WST-8 cell viability assay)
PMID21849092 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21849092/
RECORD: Rec_0332292 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Transferrin receptor-targeting peptide
7370
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
BT-474
8.8 μM
IC50 (WST-8 cell viability assay)
PMID21849092 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21849092/
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