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MYP_002499
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Basic Information
Transferrin receptor (TfR)-lytic hybrid peptide
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
32 amino acids
C179H303N47O35S
Standard
Sequence
THRPPMWSPVWPGGGKLLLKLLKKLLKLLKKK
Physicochemical Analysis
3705.68 Da
11.51
8.48
8.22
0.2649
-0.30
0.84
-0.01
22.95
118.75
0.0625
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1301.04
-2.75
45.0
46.0
125.0
262.0
9.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0182239 VERIFIED: YES
Provenance & Taxonomy
Musca domestica [Animal]
Transferrin receptor-targeting peptide
7370
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
HuCCT-1
8.3 μM
IC50
PMID21849092 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21849092/
RECORD: Rec_0193755 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0213024 VERIFIED: YES
Provenance & Taxonomy
Transferrin receptor [Animal]
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PMID21849092 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21849092/
RECORD: Rec_0215706 VERIFIED: YES
Provenance & Taxonomy
Musca domestica [Animal]
Transferrin receptor-targeting peptide
7370
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
T-47D
4.0 μM
IC50
PMID21849092 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21849092/
RECORD: Rec_0251929 VERIFIED: YES
Provenance & Taxonomy
Musca domestica [Animal]
Transferrin receptor-targeting peptide
7370
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
U-251
7.0 μM
IC50
PMID21849092 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21849092/
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