Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length191 amino acids

Chemical FormulaC964H1510N264O261S7

DescriptionStandard

        PTAHGPTLLLAVTEVVANSAAFTYFTAGALRRNFSSDMLPRQFPLQLRTKSMEVFSHELQERYPDQPMELHLWARQQPLLSCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGLVPDPEQAWTPLPVLCWTQGLPVPQVKRLETLLKFGLWLFGVPRANSKCCPHPV
    

Molecular Weight21198.37 Da

Isoelectric Point (pI)9.13

Net Charge (pH 7.0)4.46

Net Charge (pH 7.4) 4.02

Charge Density (pH 7.0) 0.0234

GRAVY Index-0.02

Hydrophobic Moment 0.55

Boman Index0.10

Instability Index45.39

Aliphatic Index 92.41

Aromaticity 0.0838

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8240.01

LogP -96.70

H-bond Donors 284.0

H-bond Acceptors 278.0

Rotatable Bonds 662.0

Heavy Atoms 1496.0

Ring Count 46.0

Amide Bonds 206.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0401731 VERIFIED: NO

Provenance & Taxonomy

OrganismHippolais icterina [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria