Peptide Database

Peptide NameRibonuclease K6 (RNase K6) (EC 3.1.27.-) (K6b) (Ribonuclease K2) (RNase K2)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length154 amino acids

Chemical FormulaC792H1224N224O210S13

DescriptionStandard

        MGPHLLGRSSLLLLLLGMWWSVRPLCAVPKGLTKARWFEIQHIQPRLLQCNKAMSGVNNYTQHCKPENTFLHNVFQDVTAVCDMPNIICKNGRHNCHQSPKPVNLTQCNFIAGRYPDCRYHDDAQYKFFIVACDPPQKTDPPYHLVPVHLDKVV
    

Molecular Weight17660.41 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)6.20

Net Charge (pH 7.4) 5.36

Charge Density (pH 7.0) 0.0402

GRAVY Index-0.27

Hydrophobic Moment 0.59

Boman Index0.02

Instability Index57.04

Aliphatic Index 82.86

Aromaticity 0.0909

Extinction Coeff. Reduced 23950.00

Extinction Coeff. Oxidized 24450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6880.92

LogP -59.53

H-bond Donors 237.0

H-bond Acceptors 238.0

Rotatable Bonds 560.0

Heavy Atoms 1239.0

Ring Count 40.0

Amide Bonds 172.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0307942 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyPancreatic ribonuclease

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Endonuclease Hydrolase Nuclease Non-hemolytic

TargetPseudomonas aeruginosa (Gram-negative)

RECORD: Rec_0377004 VERIFIED: YES