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MYP_002412
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Basic Information
Lycosin-II
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
21 amino acids
C116H189N31O25
Standard
Sequence
VWLSALKFIGKHLAKHQLSKL
Physicochemical Analysis
2417.93 Da
10.48
3.90
3.59
0.1859
0.27
0.58
0.17
3.27
134.76
0.0952
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
906.10
-3.64
32.0
31.0
83.0
172.0
5.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0146633 VERIFIED: YES
Provenance & Taxonomy
Lycosa singoriensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus cereus KCTC 1012
2 μM
MIC
PMID34506798 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34506798/
RECORD: Rec_0147312 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP32388
RECORD: Rec_0151394 VERIFIED: YES
Provenance & Taxonomy
Lycosa singoriensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii KCTC 2508
2 μM
MIC
PMID34506798 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34506798/
RECORD: Rec_0158905 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP32388
RECORD: Rec_0205689 VERIFIED: YES
Provenance & Taxonomy
Lycosa singorensis [Animal]
Lycosin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic Anti-mammalian cells
PaperToxins (Basel). 2016 Apr 26;8(5). | https://www.ncbi.nlm.nih.gov/pubmed/27128941 PMID27128941 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27128941/
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