Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC384H626N98O98S9

DescriptionStandard

        MKSLLLVLVVLVLLSCVPPVKSGPNMYIRRVFSTCWRTKGVCKKSCGKSEEYHIFCDSAFLCCIDKKYLPIQVGK
    

Molecular Weight8472.26 Da

Isoelectric Point (pI)9.35

Net Charge (pH 7.0)7.51

Net Charge (pH 7.4) 7.12

Charge Density (pH 7.0) 0.1002

GRAVY Index0.39

Hydrophobic Moment 0.80

Boman Index0.11

Instability Index54.28

Aliphatic Index 103.73

Aromaticity 0.0933

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3124.05

LogP -21.90

H-bond Donors 117.0

H-bond Acceptors 116.0

Rotatable Bonds 281.0

Heavy Atoms 589.0

Ring Count 13.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0385964 VERIFIED: NO

Provenance & Taxonomy

OrganismLeptonychotes weddellii (Weddell seal) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin