Peptide Database

Peptide NameFaricimab

Function Ontology

Anticancer

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length450 amino acids

Chemical FormulaC2192H3385N575O679S15

DescriptionStandard

        QVQLVQSGAEVAKPGTSVKLSCKASGYTFTDYWMQWVKQRPGQGLEWIGTIYPGDGDTGYAQKFQGKATLTADKSSKTVYMHLSSLASEDSAVYYCARGDYYGSNSLDYWGQGTSVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
    

Molecular Weight49137.75 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)4.54

Net Charge (pH 7.4) 3.54

Charge Density (pH 7.0) 0.0101

GRAVY Index-0.44

Hydrophobic Moment 0.55

Boman Index0.01

Instability Index41.54

Aliphatic Index 67.91

Aromaticity 0.0956

Extinction Coeff. Reduced 82280.00

Extinction Coeff. Oxidized 82905.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0139820 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyMonoclonal antibody

Tax ID9606

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPhosphorylation

Bio-Activity Profile

Function

Immunomodulatory

TargetCHO

RECORD: Rec_0244227 VERIFIED: NO

Provenance & Taxonomy

OrganismCricetulus griseus [Animal]

FamilyMonoclonal antibody

Tax ID10029

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer Immunomodulatory

Half-LifeThe terminal half life of amivantamab-vmjw is 11.3 ± 4.53 days.[L34193]

RECORD: Rec_0318694 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyMonoclonal antibody

Tax ID9606

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPhosphorylation

Bio-Activity Profile

Function

-

TargetCHO

RECORD: Rec_0427159 VERIFIED: NO

Provenance & Taxonomy

OrganismCricetulus griseus [Animal]

FamilyMonoclonal antibody

Tax ID10029

Structure & Mods

Configcyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer Immunomodulatory Enzyme replacement

TargetCHO