Peptide Database

Peptide NameHPRP-A1-iRGD

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC136H213N37O31S2

DescriptionStandard

        FKKLKKLFSKLWNWKCRGDKGPDC
    

Molecular Weight2926.51 Da

Isoelectric Point (pI)9.93

Net Charge (pH 7.0)5.74

Net Charge (pH 7.4) 5.49

Charge Density (pH 7.0) 0.2390

GRAVY Index-1.05

Hydrophobic Moment 0.77

Boman Index-0.29

Instability Index-13.90

Aliphatic Index 48.75

Aromaticity 0.1667

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1137.37

LogP -6.77

H-bond Donors 42.0

H-bond Acceptors 39.0

Rotatable Bonds 101.0

Heavy Atoms 206.0

Ring Count 7.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0304164 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetNCI-H460

Activity15.2 μM

MethodIC50

RECORD: Rec_0401423 VERIFIED: YES