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MYP_002262
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Basic Information
Amylin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitor
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
37 amino acids
C165H262N50O56S2
Standard
Sequence
KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
Physicochemical Analysis
3906.28 Da
8.90
1.83
1.54
0.0493
-0.10
0.48
0.06
1.94
68.65
0.0811
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1751.68
-27.28
63.0
61.0
126.0
273.0
4.0
43.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0037233 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
2-7
Bio-Activity Profile
Hormone
RECORD: Rec_0050686 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Calcitonin
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
2-7
Bio-Activity Profile
Hormone Calcium-regulatory peptide
Evidence URLhttps://www.uniprot.org/uniprotkb/IAPP_HUMAN/entry
RECORD: Rec_0058406 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Cell-Cell Communication
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0110154 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Inhibitor
PaperCooper G.J.S., Willis A. C., Clark A., Turner R. C., Sim R. B., Reid K. B. M.. Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients. Proc. Natl Acad. Sci. USA, 84, 8628-8632, 1987.
RECORD: Rec_0157110 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
2-7
Bio-Activity Profile
Antimicrobial
the growth of both Escherichia coli
PaperAntimicrobial activity of human islet amyloid polypeptides: an insight into amyloid peptides' connection with antimicrobial peptides.
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