Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length442 amino acids

Chemical FormulaC2238H3507N597O623S9

DescriptionStandard

        TNPGFVVRITQAGLDYAHHQAIAFLEKELAQLKLQDISGDFRVRHVGKVRYELSSLDLRSFQLPYSRISPVPNVGLQVSISNAFAAVDGDWRVKFHFIRDHGSFDLKVENVYIKINLRLGSDTSGKPTIDTSDCSTRISNVQVHFSGKFGWLYNLFYSVVESRFRKILESEVCKIVARSVRSELQPYLQTLPVTARIDARAGIDYSLVAPPVATAQSLDADLKGEFFSLAHRSAVPFPPLPLAFPPDHDRMVYFGASSYFFSTAAFAYHAAGALVFDITDSMIPKGVEFHLNTTTFSAFVPQLEKMYPKMPMKLRLSAPSAPYLNIGPEGLSLRPVVDIQAYAILPNSSLAPLFLLGLTCNVSAVIDVKSGHIVGSLKVGRMRLSLKQSDVGTFQVRTLQSIVNILTSSILLPHVNERLGEGFPLPLPERIQLSNILLRFHQ
    

Molecular Weight49033.00 Da

Isoelectric Point (pI)9.18

Net Charge (pH 7.0)7.54

Net Charge (pH 7.4) 6.56

Charge Density (pH 7.0) 0.0170

GRAVY Index0.09

Hydrophobic Moment 0.80

Boman Index0.11

Instability Index44.31

Aliphatic Index 101.22

Aromaticity 0.0995

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 31985.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0399581 VERIFIED: NO

Provenance & Taxonomy

OrganismBrachypteracias leptosomus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria