Peptide Database

Peptide NameE.Coli leader peptide of tryptophan operon

Function Ontology

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC83H127N21O17S

DescriptionStandard

        MKAIFVLKGWWRTS
    

Molecular Weight1723.09 Da

Isoelectric Point (pI)11.17

Net Charge (pH 7.0)2.50

Net Charge (pH 7.4) 2.28

Charge Density (pH 7.0) 0.1784

GRAVY Index0.21

Hydrophobic Moment 0.49

Boman Index0.17

Instability Index5.97

Aliphatic Index 83.57

Aromaticity 0.2143

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 627.60

LogP -1.56

H-bond Donors 24.0

H-bond Acceptors 21.0

Rotatable Bonds 55.0

Heavy Atoms 122.0

Ring Count 5.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0177186 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

Tax ID562

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Regulatory

MethodRadioactivity decay assay (3H) .Leader peptide is radiolabelled and then decay in radioactivity is measured.

Half-LifeNot reported, in vitro; 210 s