Peptide Database

Peptide NameyqfZ signal peptide

Function Ontology

Annotation / Sequence feature ▸ Signal peptide

Biotechnology / Production and expression ▸ Secretory enzyme production ▸ Cutinase secretion

Biotechnology / Production and expression ▸ Secretory expression optimization

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC208H332N44O52S2

DescriptionStandard

        MKRLTLVCSIVFILFILFYDLKIGTIPIQDLPVYEASA
    

Molecular Weight4345.25 Da

Isoelectric Point (pI)5.87

Net Charge (pH 7.0)-0.51

Net Charge (pH 7.4) -0.75

Charge Density (pH 7.0) -0.0134

GRAVY Index1.14

Hydrophobic Moment 0.38

Boman Index0.41

Instability Index44.81

Aliphatic Index 151.32

Aromaticity 0.1316

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1512.75

LogP -3.80

H-bond Donors 53.0

H-bond Acceptors 54.0

Rotatable Bonds 140.0

Heavy Atoms 306.0

Ring Count 7.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0030027 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilySec signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization Cutinase secretion

TargetBacillus subtilis TEB1030

MethodSecretion phenotype assay

PaperBrockmeier U, Caspers M, Freudl R, et al. Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria[J]. Journal of Molecular Biology, 2006, 362(3): 393-402. PMID16930615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16930615/