Peptide Database

Peptide NameEsculentin-2N protein

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC305H500N84O102S4

DescriptionStandard

        GTINLSFCEQERDADEEEGGEVQEEEVKRGIFSLIKGAAKVVAKGLGKEVGKFGLDLMACKVTNQC
    

Molecular Weight7103.99 Da

Isoelectric Point (pI)4.73

Net Charge (pH 7.0)-4.25

Net Charge (pH 7.4) -4.52

Charge Density (pH 7.0) -0.0643

GRAVY Index-0.32

Hydrophobic Moment 0.68

Boman Index-0.03

Instability Index29.55

Aliphatic Index 81.21

Aromaticity 0.0455

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3042.03

LogP -31.94

H-bond Donors 105.0

H-bond Acceptors 102.0

Rotatable Bonds 254.0

Heavy Atoms 495.0

Ring Count 3.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0421421 VERIFIED: NO

Provenance & Taxonomy

OrganismPelophylax nigromaculatus [Animal]

Tax ID8409

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal