Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length509 amino acids

Chemical FormulaC2561H3983N651O748S19

DescriptionStandard

        MCTKMVRVLWGCFLLWNVYISSAWTTHPGIKARATQRALDYGVQAGMEMIEQMAKERSIPDLRGSESLEFLKVDYVNYNFSNIKINAFSFPNTSLAFVPGVGIKALTNHGTANISTNWEVKSPLFQDSGGADLFLSGVYFAGILTLTRNDLGQPNLELQDCHAQVSHAHVSFSGELSVLYNSFAEPMEKPILKNLNEMGQLCPIITGEVEALNANLSMLEVLTKIDNYTLLDFSLMSSPEITENYIDLNLKGVFYPLENLADPPFSPVPFELPERSDSMLYIGISEYFFKSASFAHFAAGAFNVTLSTKEISSHLVRNSQGVGNILSRIAEIYILSQPFMVRIMATEPPVISLLPGNFTLDIPASIMLLTQSENSTAEAIVSMDFVASTSVGLVILGQRLICSLSLNRFRLSLPESNRDNIEVLRFENILSSILHFGVLPLANAKLQQGFPLPSPHKISFVNSDIEVLEHFLLISTDLKYETPLKQQPSFYGWEGLNLINGQWRGNSVP
    

Molecular Weight56469.17 Da

Isoelectric Point (pI)5.11

Net Charge (pH 7.0)-15.60

Net Charge (pH 7.4) -16.51

Charge Density (pH 7.0) -0.0306

GRAVY Index0.11

Hydrophobic Moment 0.67

Boman Index0.16

Instability Index42.87

Aliphatic Index 101.14

Aromaticity 0.0982

Extinction Coeff. Reduced 53860.00

Extinction Coeff. Oxidized 54110.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0143839 VERIFIED: NO

Provenance & Taxonomy

OrganismMyotis lucifugus [Animal]

FamilyBPI/LBP

Tax ID59463

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence