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MYP_002081
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Basic Information
D6-NH2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
10 amino acids
C70H118N28O11
Standard
Sequence
RKKRWWRRKK
Physicochemical Analysis
1527.87 Da
12.00
7.76
7.55
0.7756
-3.54
0.43
-1.45
156.16
0.00
0.2000
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
708.48
-4.22
29.0
19.0
55.0
109.0
4.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0175811 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
50 μM
MIC
PMID24056098;23860860 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24056098/
RECORD: Rec_0179462 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
antimicrobial susceptibility assay; hemolysis assay
PaperDesign of short membrane selective antimicrobial peptides containing tryptophan and arginine residues for improved activity, salt-resistance, and biocompatibility. DOI 10.1002/bit.25003; PMID 23860860. PMID23860860 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22518150/
RECORD: Rec_0183994 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa
>100 μM
MIC
PaperDesign of short membrane selective antimicrobial peptides containing tryptophan and arginine residues for improved activity, salt-resistance, and biocompatibility.
RECORD: Rec_0192656 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
6±0.012 μM
MIC
PaperDesign of short membrane selective antimicrobial peptides containing tryptophan and arginine residues for improved activity, salt-resistance, and biocompatibility. DOI 10.1002/bit.25003; PMID 23860860. PMID23860860 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22518150/
RECORD: Rec_0202101 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
12 μM
MIC
PMID24056098;23860860 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24056098/
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