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MYP_002081
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Basic Information
D6-NH2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
10 amino acids
C70H118N28O11
Standard
Sequence
RKKRWWRRKK
Physicochemical Analysis
1527.87 Da
12.00
7.76
7.55
0.7756
-3.54
0.43
-1.45
156.16
0.00
0.2000
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
708.48
-4.22
29.0
19.0
55.0
109.0
4.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0067794 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Candida albicans ATCC 10231
6 μM
MIC
PMID24056098;23860860 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24056098/
RECORD: Rec_0072654 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
3
MIC
PMID24056098;23860860 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24056098/
RECORD: Rec_0084062 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiofilm Antibacterial
Staphylococcus aureus ATCC 6538
0.0045 μM
Crystal violet assay
RECORD: Rec_0127946 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes (3% Hemolysis at 100 microM, Human erythrocytes (7% Hemolysis at 100 microM
100 μM
Hemolysis
PMID24056098;23860860 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24056098/
RECORD: Rec_0128483 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
PaperPubMed PMID: 22518150 | PubMed PMID: 23860860 PMID22518150;23860860 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22518150/
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